THE PREVALENCE OF EXTENDED-SPECTRUM BETA-LACTAMASES AND AMBLER CLASS C BETA-LACTAMASES IN ENUGU AND EBONYI STATES OF NIGERIA

Over the years, antibiotics have been among primary drugs used to treat or prevent infections in animals and humans. ESBL AmpC producing isolates become common microorganisms medical institutions. They contributed immensely clinical challenges caused by nosocomial with minimal therapeutic options.The present study investigated prevalence of extended-spectrum beta-lactamases Ambler class C Enugu Ebonyi States Nigeria. A total fifty comprising 27 23 environmental were screened observed for presence isolates. The production either two enzymes was detected observing zones inhibition diameter. findings showed samples tested. concludes that resistant bacterial (especially Gram-negatives) remain prevalent mechanism resistance beta-lactam drugs. recommends adequate appropriate detection monitoring within communities.